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Guggulsterones are beneficial compounds derived from a traditional Ayurvedic medicinal plant preparation called guggul, a gummy resin collected from the small Commiphora mukul tree. The two primary types thought to be responsible for gugglsterones' effects are Z-Guggulsterone and E-Guggulsterone.
Guggulsterones may be able to support healthy cholesterol levels and cardiovascular health.1,2 Some animal studies suggest guggulsterones may also benefit conditions like hypothyroidism in humans.3
Use as directed.
Guggul may cause stomach discomfort or allergic rash as well as other serious side effects and interactions. It should be avoided in pregnant or breast-feeding women and in children. Safety of use beyond 4 months has not been well studied.4
1. Annu Rev Nutr. 2003;23:303-13. Epub 2003 Feb 26.
2. Cardiovasc Drug Rev. 2007 Winter;25(4):375-90.
3. Phytother Res. 2005 Jan;19(1):78-80.
4. Complement Ther Med. 2005 Dec;13(4):279-90. Epub 2005 Sep 23.